Millions More Need H.I.V. Treatment, W.H.O. Says

Oct 01, 2015 · 51 comments
Lucille Hollander (Texas)
Can we have a reality check here?
MANY people in the U.S. cannot pay for medical care. MANY have Obamacare with deductibles so high that they cannot afford to be treated for anything, even HIV.
There seems to be a ton of money spent, proposals for another ton to be spent (all out of taxpayer's pockets) but many ordinary Americans and their children and families are still unable to receive health care.
HarlanR (Baltimore MD)
HIV is a behavioral disease. It is not airborne and you cannot get it simply by touching another human being in passing. It is spread by performing certain acts. It winds up in the blood supply because the people whose infected blood was donated caught it by performing certain acts. Children who get it form their mother do so because their mother performed certain acts. Chang the behavior, kill the disease. Now the liberals' head may commence exploding.
Mike (Lancaster)
Tnis is not a sustainable fix because someone else has to pay for the treatment and at some point they will want to stop paying. It may provide time to work on other more sustainable options. Another issue that people do not like to talk about is that cheap drugs from India are not always a quality product. Sometime they have lower than expected dosage to not shaving any active ingredient at all. Not all of the Indian drug comapnies work this way but you cannot tell which ones are producing a quality product from those that are not from the label or other web page.
Zahid Ali Tareen (Kot Addu-Pakistan)
HIV is happening via 'sex free society, frustration, lack of control on crimes and due to lack of awareness. Having sex is a extreme desire, so responsible societies must know how to address to control or educate people accordingly. Just distributing condoms is last solution & it is almost failed.
We must spend more on medicine research and medicine must be cheap in price and in assured availability. We must reduce budget on war and weapons. We must honestly struggle for peace and support for peace. if we want to keep this earth livable & Heaven. We must leave to living in heaven of fools.
Withheld (Lake Elmo, MN)
The last I knew, there was a significant connection between promiscuity and HIV. If I walk off a cliff, I fall into a chasm 2,000 feet below. If I chose to have irresponsible sex, I can either contract or spread HIV. If I rape someone and they get HIV, then that person has my sympathy. There is no reason to assume that everyone with HIV is an idiot, as this article assumes. To use a common analogy, instead of providing fish to the world, those of us with a brain and some education need to teach those in the dark how to fish, or at least the connection between HIV and sex. Millions of Americans have died of many causes between research money has been diverted to helping promiscuous males who know better in this country. Give me a reason to put their bad choice ahead of Alzheimer's patients or other afflicted people who did not smoke their way into lung cancer or breast cancer and did not eat their way into heart disease.
Ann LoLordo (Baltimore, Md.)
The World Health Organization’s new guidelines on immediate treatment of HIV represent a paradigm shift in managing the disease and carrying out strategies to prevent its spread. Their new recommendation for antiretroviral therapy (ART) for all people infected with HIV—without a need for further testing to determine eligibility – underscores what the research shows: that immediately starting ART for HIV upon diagnosis is better for an HIV-infected person’s own health and also reduces their risk of transmitting HIV to others. WHO’s swift translation of this latest research into global guidance for policymakers is commendable and will have broad implications for HIV public health programs throughout the world, including those supported by Jhpiego, a global health non-profit and affiliate of Johns Hopkins University, where I work. As our HIV experts Drs. Tigistu A Ashengo and Jason Reed rightly point out: "With the new ART guidelines, there are now clear recommendations from WHO that all 37 million people on Earth infected with HIV should be treated, for their health and the health of their partners. With eligibility hurdles created by health systems and policies removed, delays between diagnosis and treatment and 'rationing treatment' may be a thing of the past."
James (CA)
This recommendation, if implemented, would do nothing more than stop the epidemic in its tracks. HIV is dependent on high post infection viral loads to propagate through the population. You are not going to stop people from having sex, but you can stop them from becoming infected with disease. You could argue that it is just one more mouth to feed on a planet whose ecosystem is in peril, let them die. You could also argue that the individual you save might have the idea which saves the world. Both views are extreme. It's important to remember many women become infected against their will in societies where they have little power. How much compassion is needed to create a middle ground where people are treated and the disease is eradicated? When women are educated and given equal power, the problem of overpopulation solves itself.
Zahid Ali Tareen (Kot Addu-Pakistan)
James you are right;
There is yet dual standard in many developed societies regarding powering women.
Secondly, We cant stop people by force from having sex but we can educated them to limit having sex - with their legal partner only. We can campaign against drugs and other bad things which are life threatening but why we can not stop people on illegal sex for sake of heath and health society.
Charles (San Jose, Calif.)
News articles in recent years said certain countries in Africa were no longer allowed to get AIDS drugs from U.N. agencies, the epidemic was too far gone and the supplies were too scarce. Triage was in effect and vaccines going to only countries with successful health programs, etc. Was widely reported in the NYT.
woodwose (colorado)
I hate to point this out, but everyone that spoke positively about this change in UN guidelines stands to DIRECTLY profit from any increased spending on AIDS. They aren't drilling for oil, or selling cigarettes, but as compassionate that they may be, they are profiting from other people's misery. It reminds of a story I read in the early 90's where a twerp who worked as a caregiver taking care of AIDS patients in their last days was quoted compalining about his future employment prospects now that the AIDS drug cocktails (which were new at the time) were improving the quality and length of lives for people who had AIDS or were HIV positive. No one in the Centers for Disease Control or WHO has any real interest in seeing AIDS go away. Not when there is money to be made from it.
Ben Ryan (NYC)
You are under the delusion that the CDC and WHO are for-profit companies. You seem to be confusing these agencies with pharmaceutical companies. Furthermore, these are guidelines from WHO, not the UN. I suggest you check your facts more closely.
CJ (New York City)
And add "cancer" to that while your at it… too much to profit from if left uncured.
Girish Kotwal (Louisville, KY)
NO millions more do not need HIV antiretroviral (ART) triple therapy as soon as they are found to be HIV positive. That would be a colossal waste of millions of dollars and a definite lack of compliance resulting in increased resistance to ART. The previous WHO guidelines based on CD4 counts below 350 were far more sensible. At the most, the guidelines could be made more stringent with CD4 counts of below 500 as the acceptable starting point for triple ART. Treatment with ART requires a massive health care support to monitor patients for liver damage and other short and long term toxic effects. It is not that simple as taking aspirin or even antibiotics. There are a large number of natural broad spectrum antivirals against human viruses (Google search for this) which could be considered as the first line of treatment to prevent progression of HIV infection and only when the CD4 counts have reached below an optimal level can ART be given under medical supervision and with assurance that the drugs will not be sold by the patients as has happened in some countries.
S.L. (Briarcliff Manor, NY)
Warning: This is not PC. - Why does everyone have to pay for others' promiscuity? Those with aids are always complaining that we should do more. We are not allowed to be judgmental about the disease. They were just walking down the street and caught it. I feel sorry for the spouses who through no fault of their own are infected. I don't think it is going to be practical to treat all those infected. In the meantime, the treatment should be reserved for the victims. In Africa, women can't refuse their husbands who don't have any problem with fornicating with whomever, when the mood strikes and they don't like condoms. The Gates Foundation is funding research to invent a condom so wonderful that guys will want to use one. In the meantime, the women should be the ones to receive the drugs. Extending treatment to all will make a larger pool of those who will have a longer time to spread the disease.
Alpha Doc (Washington)
I have significant reservations about the long term effects of this many high risk people on this much Rx for decades to come.

But not because these folks will end up spreading the disease longer as you suggest. That is just wrong.

HIV POZ individuals under Rx may in fact be as safe as anyone when it comes to hiv transmission.
RC (MN)
If "untold millions" are on long-term prophylactic treatment, one question is whether the drugs and drug metabolites they excrete into the environment might pose a risk, for example to developing humans or other animals.
ejzim (21620)
Even when prophylactics are provided for free, they go unused. How can they help anyone who will not help themselves? There seems to be no way to modify behavior in these countries, not even to save their lives.
kilika (chicago)
There is a whole deal with the psychological component of being human where using behaviorism doesn't work. There are plenty of examples world wide where certain people with the Delta32-ccr gene are completely immune to this virus. Why the chemical structure of this entity isn't the model for a cure is a puzzle. This is a very complex issues. It isn't just simply they don't want to help themselves. Think India, China, Africa, etc. that are in abject poverty yet they still children. There are no easy answers.
QED (NYC)
The ccr deletion mutation would not provide a cure. It encodes a change in the physical structure of one of the receptors HIV virions use to get into T cells, preventing the virus from being able to enter the cell.
Alpha Doc (Washington)
These countries?

The hiv epidemic in the US as well as the concurrent syphilis epidemic in the US is totally about the refusal to practice safe sex by the high risk group.
California Man (West Coast)
So many of you are happy to advise spending billions on this giveaway program - as long as you don't have to pay it.

You are happy to complain miserably about the 'abusive pricing' of pharma companies, but they spent the money to build these vaccines.

You 'progressives' whine about the 'victims' of this disease, cautiously ignoring the wanton behavior of people who contract AIDS.

It's a good thing that none of you will ever be in charge.
Tired of Hypocrisy (USA)
California Man - "It's a good thing that none of you will ever be in charge."

Don't bet on that!
Jon (NM)
I'm sure that beginning in January 2017, the Tea Party-led U.S. Congress, under president Donald "I want to give to the world" Trump, will get right on this.
Chris (Battle)
I suggest people read Jon Rappaport's findings on the HIV test scam. They are notiriously inaccurate and have caused enormous harm to the people falsely disgnosed with HIV. HIV cannot lead to AIDS because AIDS is just another pharma corrupt money-spinning exercise. THe WHO are the people who declared that swine flu was a pandemic. What a lie that was and what profits were made from companies that would not allow the use of thier useless and dangerous vaccines unless they were given immunity from prosecution. That's the only immunity you will get from them. WHO should be investigated fro tgeir links to big pharma.
Dan Stackhouse (NYC)
So wait, HIV, AIDS, pharmaceutics, the swine flu, vaccines, and immunity of any kind, are all lies? And you, Chris from Battle, are the sole source of truth and wisdom? Wow, I'm sure we'll all rely on this fact-free testimonial.
Dan Stackhouse (NYC)
Sorry to be callous about it, but I don't think this is a good idea. Give people treatment for AIDS and they will inevitably spread it further. And, the earth is being gradually destroyed by the main cause of there being too many humans. Trying desperately to save millions of humans so they can double the population again in the next couple of decades seems like a self-defeating thing to do.

I know people have a lot of trouble coming to terms with this, but all humans die at some point. Keeping everyone around as long as possible only shortens the existence of humanity itself. If people can't keep their breeding in check, then famine and pestilence will be the only ways to keep the population low enough that humanity survives. War never works to decrease the population, unfortunately, as it is very popular.

I know a lot of naïve folks will yell at me over this, that's fine, but I think if the W.H.O. is going to go around saving lives, it should require vasectomies be done as a condition of the treatment. We need to cut down on population folks, and if y'all just don't get it, then humanity will cease to exist before long.
Dan Stackhouse (NYC)
And yes, I know this won't be popular, taking the coldly logical stance here. But to avert accusations of hypocrisy, I'd like to point out that I don't and won't have children, I have a very small carbon footprint (no car, don't fly often, etc.), I recycle everything I can, and I've never received nor transmitted an STD. If half of everyone lived as I do, we'd be fine environmentally speaking. On the other hand, our blog commentary sections would be a lot more inflammatory and raucous.
BostonSanFran (Brookline, MA)
The ignorance demonstrated by your comment far exceeds the callousness. First of all, we are not talking about controlling the population of fruit flies, we're talking about human beings. Second, giving people treatment is actually meant to reduce the spread of HIV - hence the proven effectiveness of PReP. You seem to imply that people who become positive will keel over and die the following day - ultimately allowing the world to be cleansed. Instead, it lies dormant for years while infected people often unknowingly infect others (including those probably not worthy of being extinguished by your line of thinking). Third, your perverse logic could be used on so many other chronic afflictions. Worth noting is that properly treated HIV+ people are typically healthy members of society who have near zero risk of infecting others. Finally, I don't even know what you're talking about regarding vasectomies as it relates to HIV. They have nothing to do with one another. If your point is simply to advocate for birth control, then have at it.
QED (NYC)
As far as I can tell, the main difference between humans and fruit flies is that fruit fly populations have natural limitations. Humans seem to spread no matter what you do.
John Perks (London England.)
We have to face the fact that sexual promiscuity is exploding into a free-for-all around the world like never before. Morals are a joke, loyalties are threadbare, and matters may only get worse. Venereal diseases are sprouting like mushrooms after a storm, as various medias around the world become more and more sex-mad. Enjoying my middle age with a great wife who's as loyal as a man can want I feel not just complacent, but happy - and feel a little sympathy for those who have to plough through the morass of sexual discovery and experimentation.
Alpha Doc (Washington)
Exploding? Hardly. I have no doubt people in the US are having a lot less sex today with a lot fewer people than we had in the 60s and 70s.

The problem in the US and other developed countries today is not the sex. It's the high risk sex group, very small in numbers, who refuse to practice safe sex and end up getting most of the new hiv Dx.

Most of the new hiv Dx in the US comes from a small high risk population group, 2-3 percent of our adult US population.
Ben Ryan (NYC)
A great move on the part of WHO, following the science that has strongly affirmed the benefits of immediate treatment for HIV. And also respecting the science increasingly showing that PrEP can lower HIV rates among high-risk populations. The big question now is money: Will major donor countries pony up the necessary billions?
thewriterstuff (MD)
If a massive campaign to people to use condoms failed, how can we be sure that we can get them to take their medicine properly? Oh yeah, more money.
Alpha Doc (Washington)
You can't. In fact you can be pretty sure that many will skip doses and many will start and stop and start again their Rx.

That is the nature of daily oral meds for any condition
frugalfish (rio de janeiro)
In Brazil, there is still a massive campaign to get people to use condoms; it hasn't failed yet, but ... AIDS is definitely on the way back up, because many believe that the new meds will save them even if they don't use condoms.
Zahid Ali Tareen (Kot Addu-Pakistan)
I think we are some little serious to control HIV.
MDP207 (NJ)
Forget the rest of the world. In our own backyard in NJ the HMOs running NJ Medicaid Expansion are DENYING medications to HIV+ patients! The federal ADAP program paid for one pill per day meds which were easy to take, and improved health outcomes (reduced viral load to undetectable – that is, no likelihood of transmission). NJ Medicaid HMOs (which are also 100% federally funded) STOPPED THAT. They require HIV+ patients to take 3 pills per day because it is cheaper. They mandate that HIV+ patients FAIL with 3 pills (that is, increase their viral load and likelihood of transmission) before the HMOs will approve 1 pill per day.

(And the bozos in NJ Medicaid allowed this to happen.)

It is not big pharma that is the problem, it is big health insurance. And what happens when government is in bed with health insurers!
FF (Baltimore)
The cost would be a heck of a lot less if we took the patents back from the pharma and stopped letting them make their monopolistic profits off the backs of the sick. And don't tell me they need these profits to develop new drugs; these HIV meds were developed at public expense. Why we should incur massive expenses and keep people sick just to insure gargantuan profits to the pharmaceutical companies is beyond me.
QED (NYC)
Wrong. The basic science was public ally funded. The translation of basic science into a drug was done by pharma companies to the tune of billions of dollars. Who do you think pays for clinical trials, ongoing safety monitoring, REMS programs, education on safe and effective use, etc.? Hint: it isn't the public sector.
Cindy (DC Metro area)
Many pharma companies have already released their patents on HIV medicines for developing countries - do a Google search for an organization called "Medicines Patent Pool"
G Seage (Boston)
Actually, the NIH has paid billions of dollars to test ARV's throughout the world (AIDS Clinical Trials Network, IMPAACT (mothers and children), HIV prevention trials network (PreP etc), HIV Microbicide Network) etc. etc. So yes, almost ALL of the ARV's that are currently in use throughout the world have been subsidized by the US taxpayers!
Justin (NYS)
So weeks after a major drug company was purchased and the prices skyrocketed, the WHO claims people now need these drugs? Is this purely a coincidence, or is someone within the WHO in bed with big pharmaceuticals?
TheTrots (Virginia)
No, this is a result of the publication of a study known as "START", which unequivocally demonstrated that ALL HIV-infected people would benefit from getting on treatment as soon as possible. And, as we also now know from many studies, treating infected people helps decrease the likelihood of spreading the virus.
Ian Grubb (New York)
Try reading the science.
ejzim (21620)
I know many generics have increased, but I think the recent uproar was about heart drugs, not HIV drugs. Most generics have gone way up in the past year. I don't think that can be blamed on the WHO.
A Martin (Lexington)
There sure is a lot of editorializing in Mr. McNeil's report about the cost of treatment without any factual information to back up such concerns. Surely preventative medicine is cheaper than treating an increased number of infected individuals? Surely there is a compelling humanitarian case to be made for action given that millions of lives are on the line? I don't think you'd see such a callous subtext in a story about the costs of treatment for cancer, Alzheimer's or heart disease.
Cindy (Tempe, AZ)
That's an apples to oranges comparison. You can't catch cancer, Alzheimer's or heart disease through unprotected activity with another person.
A Goldstein (Portland)
Treating uninfected people with anti-retroviral drugs to prevent infections will likely favor the emergence of medication-resistant strains of H.I.V. This is what happened with antibiotics when they were used used for decades to prevent or unnecessarily treat infections, giving rise to highly resistant bacteria and rendering antibiotics useless. What do we do when the same thing happens with H.I.V.?
chester west (LA)
What do we do when the strains mutate so that sex is no longer a requirement and hiv can be spread by touch or a cough or sneeze? We need to stomp this aberration out with ABC. No one gets the seriousness of it. Humans are basically proving themselves to be no better than dogs jumping a leg and will be the cause of their own demise.
swm (providence)
I think it would be fairer to compare viruses to other viruses; for instance, has the increased use of flu vaccine created untreatable strains of flu? This sounds more like a vaccination campaign, and if HIV can be prevented, then the key issues are cost, access and awareness.

With all due respect, and I mean that, creating fear about antibiotics for bacterial infections does not help the awareness raising and consideration of taking preventative measures that should happen for the prevention of HIV. Even the big bad scary MRSA (been there) can be quite treatable for a relatively healthy person with a standard course of antibiotics.
A Goldstein (Portland)
swm -
Comparing viruses to viruses, here are two of numerous references about viruses mutating and becoming drug resistant: http://www.ncbi.nlm.nih.gov/pubmed/15579088 and http://www.ncbi.nlm.nih.gov/pubmed/24152761. Whether referring to viruses, bacteria, fungi or insects, most organisms evolve resistance to chemicals designed to destroy them.